Author

Thomas Ward

Stanford MedicinePrimary ORCID profile (0000-0001-8801-747X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Thomas WardiD1 paper · UK Health Security Agency

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Alexander Eckehart UrbaniD· 2 shared Carolin PurmanniD· 2 shared Xianglong ZhangiD· 2 shared Alexis MitelpunktiD· 1 shared Arineh Khechaduri· 1 shared Bradley J. Swanson· 1 shared Bruce J. AronowiD· 1 shared ChangHui PakiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Alexander Eckehart UrbanORCID

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Author profile →

2 papers

Recent·Most cited

Cross-Platform Validation of Neurotransmitter Release Impairments in Schizophrenia Patient-Derived NRXN1-Mutant Neurons

ChangHui Pak, Tamás Dankó, Vincent R. Mirabella, Jinzhao Wang, Yingfei Liu, Madhuri Vangipuram, Sarah D. Grieder, Xianglong Zhang, Thomas Ward, Yu‐Wen Alvin Huang, Kang Jin, Phillip J. Dexheimer, Eric E. Bardes, Alexis Mitelpunkt, Junyi Ma, , Thomas Christian Südhof

This study validates that heterozygous NRXN1 deletions impair neurotransmitter release in human neurons across multiple labs, suggesting a human-specific synaptic dysfunction relevant for schizophrenia drug discovery.

Proceedings of the National Academy of Sciences · May 25, 2021Peer-reviewedNeuroscience

Local and global chromatin interactions are altered by large genomic deletions associated with human brain development

Xianglong Zhang, Ying Zhang, Xiaowei Zhu, Carolin Purmann, Michael Seamus Haney, Thomas Ward, Arineh Khechaduri, Jie Yao, Sherman M. Weissman, Alexander Eckehart Urban

The paper investigates how large genomic deletions affect chromatin interactions and states in human brain development using Hi-C and ChIP-Seq analyses.

Nature Communications · Dec 11, 2018Peer-reviewedGenetics