Structural proteomics defines a sequential priming mechanism for the progesterone receptor
Matthew D. Mann, Min Wang, Josephine C. Ferreon, Phoebe S. Tsoi, Michael P. Suess, Antrix Jain, Anna Malovannaya, Roberto Vera Alvarez, Bruce D. Pascal, Praveen Kumar, Dean P. Edwards, Patrick R. Griffin
This study uses structural mass spectrometry to reveal the sequential binding mechanism of progesterone receptor isoforms with co-regulatory proteins on target DNA.
Nature Communications · May 12, 2025Peer-reviewedBiochemistry