Phoebe S. Tsoi

This study investigates how interactions between RNA and the prion-like domain of hnRNPA1 influence aggregate morphology and infectivity in neurodegenerative diseases.

This study shows tubulin modulates Tau and synuclein condensates from pathological to physiological by promoting microtubule interactions and preventing aggregation.

This study uses structural mass spectrometry to reveal the sequential binding mechanism of progesterone receptor isoforms with co-regulatory proteins on target DNA.

This study identifies citrullination as a novel irreversible post-translational modification of TDP-43 linked to structural changes, aggregation, and pathology in TDP-43 proteinopathies.