ARMC1 regulates mitochondrial fatty acid oxidation through theinsertase/scramblase MTCH2
Andrew David Castonguay, Dariel Márquez, Andrew M. Natale, Royce York, Shelly Harel, Jack F. Cazet, Mia C. Pulos-Holmes, Angela Xu, Kibeom Kim, Katharine R. Page, Mariia Burdyniuk, Jacob N. Bonner, Yaron M. Sigal, Michael R. Paddy, Jin Chen, , Jodi M. Nunnari
This study identifies ARMC1 as a regulator of mitochondrial fatty acid oxidation through its interaction with MTCH2, showing that this interaction suppresses FAO during starvation.
bioRxiv · Aug 27, 2026 · PreprintCell Biology