Author

Michelle Vandeloo

Concordia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:large language model· 1 Assay:protein sequence· 1

Frequent Co-Authors

Aashiq Hussain KachrooiD· 1 shared Alain PacisiD· 1 shared Alysh Orr· 1 shared Anastasia Gherghi· 1 shared Andreas BergdahliD· 1 shared Andreas VillungeriD· 1 shared Angela I. Schriek· 1 shared Arthur Lindoulsi· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperSynthetic Biology

Aashiq Hussain KachrooORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

What comes after de novo? Automated lead optimization of proteins with CRADLE-1

Eli Bixby, Gino Brunner, Daniel Danciu, Richard Dela Rosa, Nicolas Deutschmann, Constance Ferragu, Franziska Geiger, Christian Holberg, Patrick Kidger, Arthur Lindoulsi, Noé Lutz, Thomas McColgan, Sebastian Millius, Harmen van Rossum, Jinel Shah, , Angela I. Schriek

CRADLE-1 automates protein lead optimization, improving speed and efficiency compared to rational design methods.

bioRxiv · Oct 16, 2026 · PreprintBioengineering

Integrated Metabolic Complex Genetic Interaction Network of Chromosome 4p Loss in Basal Breast Cancer

Lynn Karam, Alain Pacis, Rohan Dandage, Michael K. Schwartz, Gabriel Alzial, Anastasia Gherghi, Haig Hugo Vrej Djambazian, Gerardo A. Zapata, Marina A. Schapfl, Paria Asadi, Mayerly Castrillon, Alysh Orr, Belen Hernandez, Pegah Kargar, Michelle Vandeloo, , Elena Kuzmin

This study maps the metabolic complex genetic interaction network of chromosome 4p loss in basal breast cancer to identify targetable vulnerabilities.

bioRxiv · Oct 15, 2025 · PreprintGenomics

Rapid, scalable, combinatorial genome engineering by Marker-less Enrichment and Recombination of Genetically Engineered loci (MERGE)

Mudabir Abdullah, Brittany M. Greco, Jon M. Laurent, Michelle Vandeloo, Edward M. Marcotte, Aashiq Hussain Kachroo

The paper introduces MERGE, a method for marker-less, scalable genome editing in yeast by combining CRISPR-Cas9 and gene drives to efficiently integrate and combine multiple genetic edits.

bioRxiv · Jun 17, 2022 · PreprintSynthetic Biology