Different mechanisms link gain and loss of kinesin functions to axonal degeneration
Yu-Ting Liew, David M. Bailey, William Cairns, Maureece Day, Federico Dajas‐Bailador, Ella Jones, Sophie McCann, Matthias Landgraf, Lydia Lorenzo-Cisneros, Thomas Murphy, Milli Owens, Devesh C. Pant, Jill Parkin, Haydn Tortoishell, André Voelzmann, Andreas Prokop
The paper investigates how both loss and gain of kinesin functions lead to axonal degeneration through microtubule curling in Drosophila neurons.
bioRxiv · Dec 31, 2024 · PreprintNeuroscience