Author

Miriam Smith

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Ali EbrahimiD· 1 shared Aliki PerdikariiD· 1 shared Blake T. RileyiD· 1 shared D. A. KeedyiD· 1 shared Dinesh Singh ShahiD· 1 shared Elana HenningiD· 1 shared I. Sadaf FarooqiiD· 1 shared Jackson W. MorrisiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Ali EbrahimORCID

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1 paper

Recent·Most cited

Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy

Aliki Perdikari, Virgil A. Woods, Ali Ebrahim, Katherine Lawler, Rebecca Bounds, Dinesh Singh Shah, Nathanael I. Singh, Tamar Skaist Mehlman, Blake T. Riley, Shivani Sharma, Jackson W. Morris, Julia M. Keogh, Elana Henning, Miriam Smith, I. Sadaf Farooqi, D. A. Keedy

The paper identifies functional PTP1B variants in thin individuals and uses structural biology to reveal allosteric sites for obesity drug development.

Journal of Biological Chemistry · Oct 23, 2025Peer-reviewedBiophysics