Author

Mohammad Ghanem

University of Helsinki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ann-Maree Huang· 1 shared Austin R. Nelson· 1 shared Grant J. LoganiD· 1 shared Ian E. AlexanderiD· 1 shared Jane HsiiD· 1 shared Jon Zachary· 1 shared Juha T. HuiskoneniD· 1 shared Lindsay PottsiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Ann-Maree Huang

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1 paper

Recent·Most cited

Structural characterization of antibody-responses from Zolgensma treatment provides the blueprint for the engineering of an AAV capsid suitable for redosing

Mario Mietzsch, Jane Hsi, Austin R. Nelson, Neeta Khandekar, Ann-Maree Huang, Nicholas J. C. Smith, Jon Zachary, Lindsay Potts, Michelle Anne Farrar, Paul R. Chipman, Mohammad Ghanem, Ian E. Alexander, Grant J. Logan, Juha T. Huiskonen, ROBERT V. McKENNA

This study uses cryo-EM to analyze antibodies against AAV9 vectors, identifying residues that enable capsid engineering to avoid neutralization and allow redosing.

Nature Communications · Apr 19, 2025Peer-reviewedImmunology