Author

C. D. Suraweera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

M. G. Hinds· 2 shared M. Kvansakul· 2 shared A. Javorsky· 1 shared C. Giannangelo· 1 shared D. J. Creek· 1 shared D. R. Burton· 1 shared G. Siddiqui· 1 shared G. Wirjanata· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

M. G. Hinds

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity.

R. C. Edgar, G. Siddiqui, T. R. Malcolm, S. Duffy, M. Chowdhury, J. Marfurt, G. Wirjanata, R. Noviyanti, K. Daware, M. Dans, C. D. Suraweera, N. A. Counihan, R. N. Price, S. Whittlin, V. M. Avery, , S. McGowan

This paper identifies MMV1557817 as a dual aminopeptidase inhibitor effective against multiple Plasmodium species and highlights its potential as a multi-target antimalarial drug.

bioRxiv · Oct 1, 2023Microbiology

Structural insight into tanapoxvirus mediated inhibition of apoptosis

C. D. Suraweera, M. I. Anasir, S. Chugh, A. Javorsky, R. E. Impey, M. Hasan Zadeh, T. P. Soares da Costa, M. G. Hinds, M. Kvansakul

This study determines the crystal structures of TANV16L bound to Bax, Bim, and Puma BH3, revealing its mechanism of inhibiting apoptosis by adopting monomeric and dimeric forms while maintaining the canonical ligand binding groove.

The FEBS Journal · May 31, 2020Peer-reviewedMicrobiology

Crystal structures of the sheeppoxvirus encoded inhibitor of apoptosis SPPV14 bound to Hrk and Bax BH3 peptides

C. D. Suraweera, D. R. Burton, M. G. Hinds, M. Kvansakul

This study determines the crystal structures of SPPV14 bound to BH3 peptides from Bax and Hrk, revealing an ionic interaction that mimics host Bcl-2:BH3 complexes to inhibit apoptosis.

bioRxiv · Mar 10, 2020Microbiology