MicrobiologybioRxiv
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity.
R. C. Edgar, G. Siddiqui, T. R. Malcolm…·S. McGowan
This paper identifies MMV1557817 as a dual aminopeptidase inhibitor effective against multiple Plasmodium species and highlights its potential as a multi-target antimalarial drug.
DOI 10.1128/mbio.00966-24