Author

N. A. Fonseca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metagenomics· 2 Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

A. L. Guimaraes· 1 shared A. Munoz-Merida· 1 shared A. Riedel· 1 shared B. Egeter· 1 shared B. Mahata· 1 shared C. Bispo· 1 shared C. Chaves· 1 shared D. J. Adams· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPlant Biology

A. L. Guimaraes

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MIMt: A curated 16S rRNA reference database with less redundancy and higher accuracy at species-level identification

M. P. Cabezas Rodriguez, N. A. Fonseca, A. Munoz-Merida

The paper introduces MIMt, a curated 16S rRNA database that improves species-level identification accuracy and reduces redundancy compared to existing databases.

bioRxiv · Dec 15, 2023Microbiology

Idioblasts accumulating anticancer alkaloids in Catharanthus roseus leaves are a unique cell type

J. G. Guedes, R. Ribeiro, I. Carqueijeiro, A. L. Guimaraes, C. Bispo, J. Archer, H. Azevedo, N. A. Fonseca, M. Sottomayor

The paper identifies Catharanthus roseus mesophyll idioblasts as a unique cell type with a distinct transcriptomic profile and high alkaloid accumulation, offering insights into improving anticancer alkaloid production.

bioRxiv · Feb 24, 2023 · PreprintPlant Biology

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

B. Mahata, J. Pramanik, L. v. d. Weyden, K. Polanski, G. Kar, A. Riedel, X. Chen, N. A. Fonseca, K. Kundu, L. S. Campos, E. Ryder, G. Duddy, I. Walczak, K. Okkenhaug, D. J. Adams, , S. A. Teichmann

This study shows tumors induce steroid synthesis in T cells to evade immunity, and blocking this pathway restores anti-tumor immunity in mouse models.

bioRxiv · Jun 14, 2020Immunology

Speeding up the detection of invasive aquatic species using environmental DNA and nanopore sequencing

B. Egeter, J. Verissimo, M. Lopes_Lima, C. Chaves, J. Pinto, N. Riccardi, P. Beja, N. A. Fonseca

This paper develops a protocol and bioinformatic tools to improve nanopore sequencing for detecting invasive aquatic species using eDNA, demonstrating reliable detection in field samples.

bioRxiv · Jun 9, 2020 · PreprintEcology