Author

N. C. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:metagenomics· 1

Frequent Co-Authors

J. R. Chandler· 2 shared A. Berndt· 1 shared A. Gordon-Fennel· 1 shared A. K. Matarasso· 1 shared A. N. Wambua· 1 shared A. Oller· 1 shared A. Suko· 1 shared B. L. Rodriguez· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

J. R. Chandler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho-vanillin

K. E. Woods, S. Akhter, B. L. Rodriguez, K. A. Townsend, N. C. Smith, A. N. Wambua, V. Craddock, E. E. Santa, D. E. Manson, R. G. Abisado-Duque, B. R. Oakley, L. E. Hancock, Y. Miao, H. E. Blackwell, J. R. Chandler

This study evaluates benzaldehyde derivatives as quorum sensing inhibitors in Pseudomonas aeruginosa, identifying ortho-vanillin as a competitive inhibitor of RhlR.

bioRxiv · Feb 24, 2024 · PreprintMicrobiology

Cross-species activation of hydrogen cyanide production by a promiscuous quorum-sensing receptor promotes Chromobacterium subtsugae competition in a dual-species model

J. R. Chandler, C. Loo, P. Koirala, N. C. Smith, A. Oller, K. C. Evans, S. Benomar, I. R. Parisi

This study shows that promiscuous quorum-sensing receptors in Chromobacterium subtsugae allow cross-species activation of hydrogen cyanide production, giving it a competitive advantage in a dual-species model.

bioRxiv · Nov 1, 2022 · PreprintMicrobiology

Opto-MASS: a high-throughput engineering platform for genetically encoded fluorescentsensors enabling all optical in vivo detection of monoamines and neuropeptides

M. Rappleye, A. Gordon-Fennel, D. C. Castro, A. K. Matarasso, C. A. Zamorano, C. Stine, S. J. Wait, J. D. Lee, J. D. Siebart, A. Suko, N. C. Smith, J. Muster, K. A. Matreyek, D. M. Fowler, G. D. Stuber, , A. Berndt

The paper introduces Opto-MASS, a high-throughput platform for engineering fluorescent sensors to detect monoamines and neuropeptides in vivo by screening thousands of variants in mammalian cells.

bioRxiv · Jun 1, 2022 · PreprintBioengineering

Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

E. Rajendran, M. Clark, C. Goulart, B. Steinhoefel, E. T. Tjhin, N. C. Smith, K. Kirk, G. G. van Dooren

This study shows that Toxoplasma gondii regulates its arginine transporter TgApiAT1 expression in response to arginine availability, mediated by a uORF in the transcript.

bioRxiv · Oct 9, 2019Microbiology