Author

E. T. Tjhin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:plant (other)· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Spry· 2 shared E. Rajendran· 2 shared G. G. van Dooren· 2 shared K. J. Saliba· 2 shared V. M. Howieson· 2 shared A. E. Sexton· 1 shared A. G. Maier· 1 shared A. Hoegl· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

C. Spry

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Author profile →

5 papers

Recent·Most cited

Giardia intestinalis reshapes mucosal immunity toward a Type 2 response that attenuates inflammatory bowel-like diseases

A. Sardinha-Silva, P. H. Gazzinelli-Guimaraes, O. G. Ajakaye, T. R. Ferreira, E. Alves-Ferreira, E. T. Tjhin, B. Gregg, M. Y. Fink, C. H. Coelho, S. M. Singer, M. E. Grigg

This study shows Giardia intestinalis induces a Type 2 immune response that reduces inflammation in the gut, protecting against inflammatory bowel-like diseases.

bioRxiv · Mar 2, 2024 · PreprintImmunology

A novel heteromeric pantothenate kinase complex in apicomplexan parasites

E. T. Tjhin, V. M. Howieson, C. Spry, G. G. van Dooren, K. J. Saliba

The paper identifies heteromeric pantothenate kinase complexes in Plasmodium falciparum and Toxoplasma gondii, showing that PanK1 and PanK2 form functional complexes with Pf14-3-3I and are essential for parasite proliferation.

bioRxiv · Mar 16, 2021Biochemistry

Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

E. Rajendran, M. Clark, C. Goulart, B. Steinhoefel, E. T. Tjhin, N. C. Smith, K. Kirk, G. G. van Dooren

This study shows that Toxoplasma gondii regulates its arginine transporter TgApiAT1 expression in response to arginine availability, mediated by a uORF in the transcript.

bioRxiv · Oct 9, 2019Microbiology

Identification of a divergent cytochrome c oxidase complex in the mitochondrial proteome of Toxoplasma gondii

A. Seidi, L. S. Muellner-Wong, E. Rajendran, E. T. Tjhin, L. Dagley, V. Y. T. Aw, A. Webb, C. J. Tonkin, G. van Dooren

The paper identifies a divergent cytochrome c oxidase complex in Toxoplasma gondii mitochondria, revealing unique proteins essential for parasite survival.

bioRxiv · May 11, 2018Microbiology

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues

E. T. Tjhin, C. Spry, A. L. Sewell, A. Hoegl, L. Barnard, A. E. Sexton, V. M. Howieson, A. G. Maier, D. J. Creek, E. Strauss, R. Marquez, K. Auclair, K. J. Saliba

The paper identifies mutations in Plasmodium falciparum pantothenate kinase genes that confer resistance to pantothenate analogues and reveal different mechanisms of action for these compounds.

bioRxiv · Jul 24, 2017Pharmacology & Toxicology