Author

R. Kappagantula

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Hayashi· 3 shared A. P. Makohon-Moore· 3 shared C. A. Iacobuzio-Donahue· 3 shared J. Hong· 3 shared L. Zhang· 3 shared H. Sakamoto· 2 shared J. Huang· 2 shared M. A. Attiyeh· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Hayashi

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Author profile →

3 papers

Recent·Most cited

Evolutionary Dynamics of Non-Coding Regions in Pancreatic Ductal Adenocarcinoma

A. Hayashi, Y.-j. Ho, A. P. Makohon-Moore, A. Zucker, J. Hong, J. G. Reiter, J. Huang, L. Zhang, M. A. Attiyeh, P. Baez, R. Kappagantula, J. P. Melchor, E. M. OReilly, N. D. Socci, S. Oki, , C. A. Iacobuzio-Donahue

This study investigates the evolutionary dynamics of non-coding regions in pancreatic cancer, finding higher mutational burden in noncoding DNA and similar mutational spectra between enhancers and coding DNA.

bioRxiv · Sep 11, 2020 · PreprintCancer Biology

Evolutionary Origins of Recurrent Pancreatic Cancer

H. Sakamoto, M. Attiyeh, J. Gerold, A. P. Makohon-Moore, A. Hayashi, J. Hong, R. Kappagantula, L. Zhang, J. Melchor, J. Reiter, A. Heyde, C. Bielski, A. Penson, D. Chakravarty, E. O'Reilly, , C. A. Iacobuzio-Donahue

This study identifies genetic features of recurrent pancreatic cancer through sequencing and finds that treatment-induced genetic changes and potential second primary tumors influence recurrence.

bioRxiv · Oct 31, 2019Cancer Biology

The Genetic Basis of Transcriptional and Spatial Heterogeneity of Basal-Like Features in Pancreatic Ductal Adenocarcinoma

A. Hayashi, J. Fan, R. Chen, Y.-j. Ho, A. P. Makohon-Moore, Y. Zhong, J. Hong, H. Sakamoto, M. A. Attiyeh, Z. A. Kohutek, L. Zhang, J. Huang, A. Boumiza, R. Kappagantula, P. Baez, , C. A. Iacobuzio-Donahue

The paper identifies genetic and transcriptional features of basal-like subtypes in pancreatic ductal adenocarcinoma, linking them to squamous histology and chromatin modifier mutations.

bioRxiv · Apr 4, 2019 · PreprintCancer Biology