Author

N. Darabedian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. R. Pratt· 2 shared A. R. Batt· 1 shared E. T. Chouchani· 1 shared H. Xiao· 1 shared H.-G. Sprenger· 1 shared J. Che· 1 shared J. J. Kohler· 1 shared J. Petrocelli· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

M. R. Pratt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A comprehensive landscape of the zinc-regulated human proteome

N. Burger, M. Mittenbuhler, H. Xiao, S. Shin, L. Bozi, S. Wei, H.-G. Sprenger, Y. Sun, Y. Zhu, N. Darabedian, J. Petrocelli, P. Latorre Muro, J. Che, E. T. Chouchani

This study maps zinc-regulated cysteine sites in the human proteome, identifies cancer dependencies, and reveals a mechanism of zinc-induced cytotoxicity in lung cancers.

bioRxiv · Jan 4, 2024 · PreprintCell Biology

Exo-enzymatic addition of diazirine-modified sialic acid to cell surfaces enables photocrosslinking of glycoproteins

N. Yarravarapu, R. S. R. Konada, N. Darabedian, N. J. Pedowtiz, S. N. Krishnamurthy, M. R. Pratt, J. J. Kohler

The paper introduces an exo-enzymatic method to add diazirine-modified sialic acid to cell surfaces, enabling UV-induced crosslinking of glycoproteins involved in glycan-mediated interactions.

bioRxiv · Oct 7, 2021Biochemistry

MYPT1 O-GlcNAc modification controls the sensitivity of fibroblasts to sphingosine-1-phosphate mediated cellular contraction

N. J. Pedowitz, A. R. Batt, N. Darabedian, M. R. Pratt

This study shows that MYPT1 O-GlcNAc modification regulates fibroblast sensitivity to S1P-induced contraction by inhibiting MYPT1 phosphorylation and MLC dephosphorylation, impacting wound healing.

bioRxiv · Jun 24, 2020 · PreprintCell Biology