Author

N. Devasahayam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

G. V. Chandramouli· 3 shared J. R. Brender· 3 shared K. Yamamoto· 3 shared M. C. Krishna· 3 shared S. Kishimoto· 3 shared Y. Otowa· 3 shared J. B. Mitchell· 2 shared K. Yamashita· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersCancer Biology

G. V. Chandramouli

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3 papers

Recent·Most cited

Evofosfamide and Gemcitabine Act Synergistically in Pancreatic Cancer Xenografts by Dual Action on Tumor Vasculature and Inhibition of Homologous Recombination DNA Repair

Y. Otowa, S. Kishimoto, Y. Saida, K. Yamashita, K. Yamamoto, G. V. Chandramouli, N. Devasahayam, J. B. Mitchell, M. C. Krishna, J. R. Brender

This study shows that evofosfamide and gemcitabine work together in pancreatic cancer xenografts by improving tumor oxygenation and inhibiting DNA repair, with effects varying by tumor type.

Antioxidants & Redox Signaling · Sep 1, 2023Peer-reviewedCancer Biology

Evaluation of a deuterated triarylmethyl spin probe for in vivo R2*-based EPR oximetric imaging with enhanced dynamic range

S. Kishimoto, N. Devasahayam, G. V. Chandramouli, R. Murugesan, Y. Otowa, K. Yamashita, K. Yamamoto, J. R. Brender, M. C. Krishna

This study compares two spin probes for oxygen measurement in vivo, finding Ox071 more sensitive and capable of a broader pO2 range.

bioRxiv · May 18, 2023Biophysics

PEGPH20, a PEGylated Human Hyaluronidase, Induces Radiosensitization by Reoxygenation In Pancreatic Cancer Xenografts. A Molecular Imaging Study

T. Seki, Y. Saida, S. Kishimoto, J. Lee, Y. Otowa, K. Yamamoto, G. V. Chandramouli, N. Devasahayam, J. B. Mitchell, J. R. Brender, M. C. Krishna

This study shows PEGPH20 improves radiation therapy efficacy in pancreatic cancer tumors with high hyaluronan by increasing oxygenation, as measured by multiple imaging techniques.

bioRxiv · Jan 11, 2022Cancer Biology