Decreased sarcomeric mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin action in type 2 diabetes
D. Rizo-Roca, D. S. Guimaraes, L. A. Pendergrast, N. Di Leo, A. V. Chibalin, S. Maqdasy, M. Ryden, E. Naslund, J. R. Zierath, A. Krook
The paper shows that reduced CKMT2 impairs mitochondrial function in type 2 diabetes, independent of insulin action.
bioRxiv · Jan 11, 2024 · PreprintPhysiology