Author

N. E. Scharping

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. C. Poholek· 1 shared A. Ferry· 1 shared A. Monell· 1 shared A. T. Frisch· 1 shared A. W. Goldrath· 1 shared B. Boland· 1 shared B. R. Ford· 1 shared C. S. Indralingam· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. C. Poholek

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2 papers

Recent·Most cited

Functional Diversity of Memory CD8 T Cells is Spatiotemporally Imprinted

M. Reina-Campos, A. Monell, A. Ferry, V. Luna, K. Cheung, G. Galletti, N. E. Scharping, K. Takehara, S. Quon, B. Boland, Y. H. Lin, W. H. Wong, C. S. Indralingam, G. W. Yeo, J. T. Chang, , A. W. Goldrath

The paper investigates how spatial location influences the functional diversity of memory CD8 T cells by analyzing their transcriptomes in the small intestine.

bioRxiv · Mar 20, 2024Immunology

Altered costimulatory signals and hypoxia support chromatin landscapes limiting the functional potential of exhausted T cells in cancer

B. R. Ford, N. L. Rittenhouse, N. E. Scharping, P. D. A. Vignali, A. T. Frisch, R. Peralta, G. M. Delgoffe, A. C. Poholek

This study identifies epigenetic changes in exhausted T cells during tumor infiltration, showing they are driven by altered costimulatory signals and hypoxia, which limit their transcriptional potential.

bioRxiv · Jul 11, 2021 · PreprintImmunology