Author

N. Hurst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. P. Kalverda· 1 shared A. Zhuravleva· 1 shared B. Chen· 1 shared C. A. Peloquin· 1 shared C. Nys· 1 shared G. Grey· 1 shared I. W. Manfield· 1 shared J. Liu· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. P. Kalverda

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Molecular chaperone BiP controls activity of the ER stress sensor Ire1 through interactions with its oligomers

S. Dawes, N. Hurst, G. Grey, L. Wieteska, N. V. Wright, I. W. Manfield, M. H. Hussain, A. P. Kalverda, J. R. Lewandowski, B. Chen, A. Zhuravleva

This study shows BiP directly interacts with Ire1 oligomers to regulate its activation, controlling ER stress response by modulating Ire1-LD oligomerization.

bioRxiv · Feb 16, 2024 · PreprintBiophysics

Use of Therapeutic Drug Monitoring to Characterize Cefepime-Induced Neurotoxicity

V. Venugopalan, C. Nys, N. Hurst, Y. Chen, M. Bruzzone, K. Cherabuddi, N. M. Iovine, J. Liu, M. H. Al-Shaer, M. H. Scheetz, N. J. Rhodes, C. A. Peloquin, K. P. Klinker

This study evaluates cefepime-induced neurotoxicity by analyzing trough concentrations, clinical factors, and EEG findings in hospitalized patients.

bioRxiv · Aug 13, 2020 · PreprintPharmacology & Toxicology