Author

C. S. Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

I. Gori· 2 shared A. B. Evans· 1 shared A. Purkiss· 1 shared B. Schmierer· 1 shared C. S. Lewis· 1 shared D. Joshi· 1 shared D. Ojha· 1 shared D. R. Squair· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

I. Gori

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

N4-Hydroxycytidine/Molnupiravir Inhibits RNA-Virus Induced Encephalitis by Producing Mutated Viruses with Reduced Fitness

D. Ojha, C. S. Hill, S. Zhou, A. B. Evans, J. M. Leung, C. S. Lewis, F. Amblard, R. F. Schinazi, R. S. Baric, K. E. Peterson, R. Swanstrom

This study shows that N4-hydroxycytidine and its prodrug molnupiravir reduce RNA-virus-induced encephalitis by producing less fit viruses with G-to-A and C-to-U mutations.

bioRxiv · Aug 22, 2023 · PreprintMicrobiology

Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

I. Gori, R. George, A. Purkiss, S. Strohbuecker, R. A. Randall, R. Ogrodowicz, V. Carmignac, L. Faivre, D. Joshi, S. Kjaer, C. S. Hill

This study shows that SGS mutations in SKI prevent its binding to phosphorylated SMAD2/3, leading to SKI stabilization and reduced TGF-β responses.

bioRxiv · Oct 7, 2020Biochemistry

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses

L. D. Hutchinson, N. J. Darling, S. Nicolaou, I. Gori, D. R. Squair, P. Cohen, C. S. Hill, G. P. Sapkota

The paper identifies salt-inducible kinases (SIKs) as regulators of TGFβ-mediated transcriptional and apoptotic responses through pharmacological and genetic approaches.

bioRxiv · Oct 17, 2019Cancer Biology

TGF-β family ligands exhibit distinct signaling dynamics that are driven by receptor localization

D. S. J. Miller, B. Schmierer, C. S. Hill

The paper shows that TGF-β family ligands have distinct signaling dynamics due to differences in receptor localization and internalization, driven by ligand-receptor affinity.

bioRxiv · Mar 1, 2019Cell Biology