Author

N. Kumari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Dhanwal· 1 shared A. Ivanov· 1 shared A. Kumar· 1 shared A. M. Owens· 1 shared A. N. Bhatt· 1 shared A. van der Vaart· 1 shared A. Verma· 1 shared B. T. Ugaz· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Dhanwal

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Elucidation of the essentiality of lumazine synthase (RibH) for Mycobacterium tuberculosis survival and discovery of potent inhibitors for enhanced antimycobacterial therapy

M. Singh, A. Dhanwal, A. Verma, L. Augustin, N. Kumari, S. Chakraborti, N. Agarwal, D. Sriram, R. J. Dey

This study validates the essentiality of RibH in M. tb survival and identifies three potent RibH inhibitors that show antimycobacterial activity and synergy with first-line TB drugs.

bioRxiv · Jul 18, 2023 · PreprintMicrobiology

Uracil-DNA glycosylase efficiency is modulated by substrate rigidity

P. B. Orndorff, S. Poddar, A. M. Owens, B. T. Ugaz, N. Kumari, S. Amin, W. D. Van Horn, A. van der Vaart, M. Levitus

This study shows that uracil-DNA glycosylase efficiency is determined by substrate flexibility, with more flexible DNA sequences showing higher enzyme activity.

bioRxiv · Aug 30, 2022Biophysics

Glycolytic inhibitor 2-Deoxy-D-glucose attenuates SARS-CoV-2 multiplication in host cells and weakens the infective potential of progeny virions

A. N. Bhatt, A. Kumar, Y. Rai, N. Kumari, D. Vedagiri, K. H. Harshan, V. Chinnadurai, S. Chandna

This study shows that 2-Deoxy-D-glucose inhibits SARS-CoV-2 replication by blocking glycolysis and causing unglycosylation of the spike protein, reducing viral infectivity.

bioRxiv · Jun 12, 2021Cell Biology

Velcro-like mannose and slime-like sialic acid interactions guide self- adhesion and aggregation of virus N-glycan shields

E. Ogharandunkun, W. Tewolde, E. Damtae, S. Wang, A. Ivanov, N. Kumari, S. Nekhai, P. Chandran

This study investigates how slime-like and Velcro-like interactions between sialic acid and mannose residues in N-glycan shields on viruses influence self-adhesion and aggregation.

bioRxiv · May 1, 2020 · PreprintBiophysics

Presence of polyadenylated 3' tail in RNA of Pepper mild mottle virus allows the Oligo(dT)18 in Priming cDNA Synthesis of its genomic RNA template

N. Kumari, V. Sharma, S. Choudhary, P. N. Sharma

This study shows that Pepper mild mottle virus (PMMoV) genomic RNA has polyadenylated 3' tails, allowing oligo(dT)18 priming despite lacking poly(A) tails in its 3' UTR.

bioRxiv · Apr 13, 2020 · PreprintPathology