Author

A. Moradian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Biophysics· 2 Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Assay:proteomics· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

M. J. Sweredoski· 5 shared J. B. Kinney· 2 shared N. M. Belliveau· 2 shared R. Phillips· 2 shared S. Hess· 2 shared W. T. Ireland· 2 shared , A. Binek· 1 shared A. Gagliardi· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersBiophysics

M. J. Sweredoski

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

An inflection point in high-throughput proteomics with Orbitrap Astral: analysis of biofluids, cells, and tissues

N. G. Hendricks, S. D. Bhosale, A. J. Keoseyan, J. Ortiz, A. Stotland, S. Seyedmohammad, C. D. L. Nguyen, J. Bui, A. Moradian, S. M. Mockus, J. E. Van Eyk

This paper introduces a high-throughput proteomics workflow using Orbitrap and Astral mass analyzers, demonstrating robust sample preparation and high protein identification rates across diverse biological samples.

bioRxiv · Apr 26, 2024Biochemistry

Functional glycoproteomics by integrated network assembly and partitioning

M. E. Griffin, J. W. Thompson, Y. Xiao, M. J. Sweredoski, E. H. Jensen, Y. Koldobskaya, A. L. Schacht, T. D. Kim, P. Choudhry, B. Lomenick, S. D. Garbis, A. Moradian, L. C. Hsieh-Wilson

This paper introduces a systems-level approach to study O-GlcNAcylation by integrating AP-MS and chemoproteomics with network analysis, revealing both conserved and tissue-specific functions.

bioRxiv · Jun 13, 2023 · PreprintCell Biology

Multi-omic analysis of CIC's functional networks reveals novel interaction partners and a potential role in mitotic fidelity

Y. Takemon, V. G. LeBlanc, J. Song, S. Y. Chan, S. D. Lee, D. L. Trinh, S. T. Ahmad, W. R. Brothers, R. D. Corbett, A. Gagliardi, A. Moradian, J. G. Cairncross, S. Yip, S. A. Aparicio, J. A. Chan, , M. A. Marra

This study uses multi-omic approaches to analyze CIC's functional networks, identifying novel interactions and revealing its role in mitotic fidelity and transcriptional splicing.

bioRxiv · Apr 6, 2023Cancer Biology

Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology

J. A. Griffiths, B. B. Yoo, P. Thuy-Boun, V. Cantu, K. Weldon, C. Challis, M. J. Sweredoski, K. Y. Chan, T. M. Thron, G. Sharon, A. Moradian, G. Humphrey, Q. Zhu, J. Shaffer, D. W. Wolan, , S. Mazmanian

This study activates specific gut neurons in mice to show they influence microbiome structure and gut physiology, including bile acids and fecal output, without brain signals.

bioRxiv · Apr 12, 2021Physiology

Standardized workflow for precise mid- and high-throughput proteomics of blood biofluids

A. Mc Ardle, , A. Binek, A. Moradian, B. Chazarin Orgel, A. Rivas, K. E. Washington, C. Phebus, D.-M. Manalo, J. Go, V. Venkatraman, C. Johnson, Q. Fu, S. Cheng, K. Raedschelders, J. Fert-Bober, , J. E. VanEyk

The paper develops a standardized proteomics workflow for high- and mid-throughput analysis of blood biofluids, showing reliable protein detection across different matrices.

bioRxiv · Mar 26, 2021Biochemistry

Deciphering the regulatory genome of Escherichiacoli, one hundred promoters at a time

W. T. Ireland, S. M. Beeler, E. Flores-Bautista, N. M. Belliveau, M. J. Sweredoski, A. Moradian, J. B. Kinney, R. Phillips

The paper introduces a method to characterize promoter regulation in E. coli by analyzing 100 promoters across 12 growth conditions, identifying regulatory elements and transcription factors.

bioRxiv · Jan 18, 2020Biophysics

Single subunit degradation of WIZ, a lenalidomide- and pomalidomide dependent substrate of E3 ubiquitin ligase CRL4CRBN

H. H. Yu, J. M. Reitsma, M. J. Sweredoski, A. Moradian, S. Hess, R. J. Deshaies

This study identifies WIZ as a novel substrate of the CRL4CRBN E3 ubiquitin ligase complex that is degraded by lenalidomide and pomalidomide, highlighting the mechanism of IMiD-induced protein degradation.

bioRxiv · Apr 2, 2019 · PreprintBiochemistry

A systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria

N. M. Belliveau, S. L. Barnes, W. T. Ireland, D. L. Jones, M. J. Sweredoski, A. Moradian, S. Hess, J. B. Kinney, R. Phillips

The paper introduces a systematic method combining assays and modeling to dissect bacterial promoter mechanisms at nucleotide resolution.

bioRxiv · Jan 6, 2018Biophysics