Author

M. J. Sweredoski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:development & morphogenesis· 3 Research Focus:cell type annotation· 2 Organism:E. coli· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

A. Moradian· 5 shared J. B. Kinney· 2 shared N. M. Belliveau· 2 shared R. Phillips· 2 shared S. Hess· 2 shared W. T. Ireland· 2 shared A. L. Schacht· 1 shared B. B. Yoo· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersBiophysics

A. Moradian

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Author profile →

6 papers

Recent·Most cited

Functional glycoproteomics by integrated network assembly and partitioning

M. E. Griffin, J. W. Thompson, Y. Xiao, M. J. Sweredoski, E. H. Jensen, Y. Koldobskaya, A. L. Schacht, T. D. Kim, P. Choudhry, B. Lomenick, S. D. Garbis, A. Moradian, L. C. Hsieh-Wilson

This paper introduces a systems-level approach to study O-GlcNAcylation by integrating AP-MS and chemoproteomics with network analysis, revealing both conserved and tissue-specific functions.

bioRxiv · Jun 13, 2023 · PreprintCell Biology

Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology

J. A. Griffiths, B. B. Yoo, P. Thuy-Boun, V. Cantu, K. Weldon, C. Challis, M. J. Sweredoski, K. Y. Chan, T. M. Thron, G. Sharon, A. Moradian, G. Humphrey, Q. Zhu, J. Shaffer, D. W. Wolan, , S. Mazmanian

This study activates specific gut neurons in mice to show they influence microbiome structure and gut physiology, including bile acids and fecal output, without brain signals.

bioRxiv · Apr 12, 2021Physiology

Deciphering the regulatory genome of Escherichiacoli, one hundred promoters at a time

W. T. Ireland, S. M. Beeler, E. Flores-Bautista, N. M. Belliveau, M. J. Sweredoski, A. Moradian, J. B. Kinney, R. Phillips

The paper introduces a method to characterize promoter regulation in E. coli by analyzing 100 promoters across 12 growth conditions, identifying regulatory elements and transcription factors.

bioRxiv · Jan 18, 2020Biophysics

Bacterial flagellar motor PL-ring disassembly sub-complexes are widespread and ancient

M. Kaplan, M. J. Sweredoski, J. Rodrigues, E. I. Tocheva, Y.-W. Chang, D. R. Ortega, M. Beeby, G. J. Jensen

The paper shows that bacterial flagellar motor PL-ring sub-complexes persist after disassembly across multiple phyla and are ancient, not recently transferred.

bioRxiv · Sep 30, 2019Evolutionary Biology

Single subunit degradation of WIZ, a lenalidomide- and pomalidomide dependent substrate of E3 ubiquitin ligase CRL4CRBN

H. H. Yu, J. M. Reitsma, M. J. Sweredoski, A. Moradian, S. Hess, R. J. Deshaies

This study identifies WIZ as a novel substrate of the CRL4CRBN E3 ubiquitin ligase complex that is degraded by lenalidomide and pomalidomide, highlighting the mechanism of IMiD-induced protein degradation.

bioRxiv · Apr 2, 2019 · PreprintBiochemistry

A systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria

N. M. Belliveau, S. L. Barnes, W. T. Ireland, D. L. Jones, M. J. Sweredoski, A. Moradian, S. Hess, J. B. Kinney, R. Phillips

The paper introduces a systematic method combining assays and modeling to dissect bacterial promoter mechanisms at nucleotide resolution.

bioRxiv · Jan 6, 2018Biophysics