Author

N. Malats

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

F. X. Real· 4 shared A. Cayuela-Lopez· 1 shared A. de Reynies· 1 shared A. Font· 1 shared A. G. Robertson· 1 shared A. Hartmann· 1 shared A. Kamoun· 1 shared A. M. Schlitter· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersCancer Biology

F. X. Real

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Author profile →

4 papers

Recent·Most cited

A common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

C. Bodas, I. Felipe, B. Chanez, M. Lafarga, E. Lopez-de-Maturana, J. Martinez-de-Villarreal, N. del Pozo, M. Malumbres, P. Vargiu, A. Cayuela-Lopez, I. Peset, K. E. Connelly, J. Hoskins, R. Mendez, L. E. Amundadottir, , F. X. Real

This paper shows a CTRB2 deletion variant increases pancreatic cancer risk by causing ER stress and inflammation in mice, using a new genetic model.

bioRxiv · Jul 23, 2024Cancer Biology

GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinoma

M. P. de Andres, R. Jackson, C. Pilarsky, A. M. Schlitter, E. Costello, W. Greenhalf, P. Ganeh, T. Knoesel, D. Palmer, P. Ruemmele, W. Weichert, M. Buechler, T. Hackert, J. P. Neoptolemos, N. Malats, , F. X. Real

This study shows that low GATA4 and GATA6 expression in pancreatic ductal adenocarcinoma (PDAC) is linked to worse patient outcomes and loss of the classical tumor phenotype.

bioRxiv · Aug 9, 2021Cancer Biology

Immunohistochemistry-based taxonomical classification of bladder cancer predicts response to neoadjuvant chemotherapy

A. Font, M. Domenech, R. Benitez, M. Rava, M. Marques, J. L. Ramirez, S. Pineda, S. Dominguez, J. L. Gago, J. Badal, C. Carrato, H. Lopez, A. Quer, D. Castellano, N. Malats, F. X. Real

This paper shows that immunohistochemical classification of bladder cancer tumors predicts response to neoadjuvant chemotherapy, with BASQ-like tumors showing higher likelihood of complete response.

bioRxiv · Aug 5, 2019Pathology

A consensus molecular classification of muscle-invasive bladder cancer

A. Kamoun, A. de Reynies, Y. Allory, G. Sjodahl, A. G. Robertson, R. Seiler, K. Hoadley, H. Al-Ahmadie, W. Choi, C. S. Groeneveld, M. A. A. Castro, J. Fontugne, P. Eriksson, Q. Mo, J. Kardos, , The Bladder Cancer Molecular Taxonomy Group

The paper identifies six consensus molecular classes of muscle-invasive bladder cancer using transcriptomic data and classification systems, providing a framework for future biomarker validation.

bioRxiv · Apr 27, 2019Cancer Biology