N. McArthur

Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils

This paper describes a FACS method using quantum dots to isolate high-quality conformational antibodies against insoluble antigens like amyloid fibrils.

Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates

This study selects conformational nanobodies specific for aggregated tau using flow cytometry, showing their utility in detecting tau aggregates in mouse and human samples.

Experimental and analytical framework for ''mix-and-read'' assays based on split luciferase

This paper develops a 'mix-and-read' assay using split luciferase for sensitive detection and quantification of analytes in solution, with a model to predict assay performance.

Quantitative yeast-yeast two hybrid for discovery and binding affinity estimation of protein-protein interactions

This paper introduces a quantitative yeast-yeast two hybrid system to discover and estimate binding affinities of protein-protein interactions.