Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils
A. A. Desai, J. M. Zupancic, H. Trzeciakiewicz, J. E. Gerson, K. N. DuBois, M. E. Skinner, L. M. Sharkey, N. McArthur, S. P. Ferris, N. N. Bhatt, E. K. Makowski, M. D. Smith, H. Chen, J. Huang, C. Jerez, , P. M. Tessier
This paper describes a FACS method using quantum dots to isolate high-quality conformational antibodies against insoluble antigens like amyloid fibrils.
bioRxiv · Jul 4, 2023 · PreprintBioengineering