Author

N. N. Laqtom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

M. Abu-Remaileh· 2 shared A. Ejima· 1 shared A. R. Mehdipour· 1 shared A. S. Rosato· 1 shared B. Gasnier· 1 shared C. Debacker· 1 shared C. Grimm· 1 shared C. Low· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

M. Abu-Remaileh

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2 papers

Recent·Most cited

MFSD1 in complex with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes

K. E. J. Jungnickel, O. Guelle, M. Iguchi, W. Dong, V. Kotov, F. Gabriel, C. Debacker, J. Dairou, I. McCort-Tranchepain, N. N. Laqtom, S. H. Chan, A. Ejima, K. Sato, D. Massa Lopez, P. Saftig, , M. Damme

The paper identifies MFSD1 as a lysosomal dipeptide uniporter that facilitates the transport of cationic and neutral dipeptides when amino acid exporters are overloaded.

Nature Cell Biology · Jun 5, 2024Peer-reviewedBiochemistry

TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells

D. Wuenkhaus, R. Tang, K. Nyame, N. N. Laqtom, M. Schweizer, A. S. Rosato, E. K. Kroegsaeter, C. Wollnik, M. Abu-Remaileh, C. Grimm, G. Hermey, R. Kuhn, D. Gruber-Schoffnegger, S. Markmann

This study shows TRPML1 activation reduces lysosomal storage in CLN3-deficient retinal cells but does not restore BMP levels.

bioRxiv · Jun 21, 2023Cell Biology