Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis
M. Sasaki, T. Hara, J. X. Wang, Y. Zhou, K. V. Kennedy, N. N. Umeweni, M. A. Alston, Z. C. Spergel, R. Nakagawa, E. A. McMillan, K. A. Whelan, T. A. Karakasheva, K. E. Hamilton, M. A. Ruffner, A. B. Muir
This study shows LOX promotes epithelial differentiation and barrier integrity in EoE by activating the BMP pathway through increased BMP2 and reduced follistatin.
Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2024Peer-reviewedCell Biology