Author

R. Sanders

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Plant Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Assay:proteomics· 6 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:plant (other)· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Hendrix· 2 shared G. de Bree· 2 shared G. Vidarsson· 2 shared J. Deikman· 2 shared M. van Gils· 2 shared P. Brouwer· 2 shared T. Caniels· 2 shared W. Zheng· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersPlant Biology

B. Hendrix

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Heavy-chain CDR3-engineered B cells facilitate in vivo evaluation of HIV-1 vaccine candidates

W. He, T. Ou, N. Skamangas, C. Bailey, N. Bronkema, Y. Guo, Y. Yin, V. Kobzarenko, X. Zhang, A. Pan, X. Liu, A. Allwardt, D. Mitra, B. Quinlan, R. Sanders, , M. Farzan

The paper evaluates HIV-1 vaccine candidates using HCDR3-engineered B cells, finding that SOSIP-TM mRNA-lipid nanoparticles induce stronger anti-apex responses than multimerized SOSIP proteins.

bioRxiv · Nov 7, 2022 · PreprintImmunology

Evaluation of plasma N-terminal pro-B-type natriuretic peptide levels in healthy North American Salukis with normal echocardiographic measurements.

T. Gunasekaran, C. Brennan, R. Sanders

This study evaluates NT-proBNP reference limits in healthy Salukis and finds the upper limit is within the non-breed-specific range, supporting current cut-off values for clinical use.

bioRxiv · Nov 3, 2021Physiology

Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva

T. J. Ketas, D. Chaturbhuj, V. Cruz Portillo, E. Francomano, E. Golden, S. Chandrasekhar, G. Debnath, R. Diaz Tapia, A. Yasmeen, W. Leconet, Z. Zhao, P. J. M. Brouwer, M. M. Cushing, R. Sanders, A. Cupo, , J. P. Moore

This study detects S-protein and RBD-specific antibodies in saliva from mRNA-vaccinated healthcare workers after their second dose.

bioRxiv · Mar 11, 2021Microbiology

High transgene expression is associated with systemic GFP silencing in Nicotiana benthamiana

B. Hendrix, P. Hoffer, R. Sanders, S. Schwartz, W. Zheng, B. Eads, D. Taylor, J. Deikman

This study shows that high transgene expression in Nicotiana benthamiana enables systemic gene silencing, while a partial transposase sequence does not affect this process.

bioRxiv · Jan 4, 2021Plant Biology

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

W. Hoepel, H.-J. Chen, S. Allahverdiyeva, X. Manz, J. Aman, P. Bonta, P. Brouwer, S. de Taeye, T. Caniels, K. van der Straten, K. Golebski, G. Griffith, R. Jonkers, M. Larsen, F. Linty, , J. den Dunnen

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients induces hyper-inflammatory responses in macrophages, leading to endothelial barrier breakdown and microvascular thrombosis.

bioRxiv · Jul 13, 2020Immunology

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

P. Brouwer, T. Caniels, K. van Straten, J. Snitselaar, Y. Aldon, S. Bangaru, J. Torres, N. Okba, M. Claireaux, G. Kerster, A. Bentlage, M. van Haaren, D. Guerra, J. Burger, E. Schermer, , M. van Gils

This study isolates potent neutralizing antibodies from COVID-19 patients that target multiple sites on the SARS-CoV-2 spike protein, offering insights for vaccine design and therapeutic development.

bioRxiv · May 12, 2020Microbiology

Topically delivered 22 nt siRNAs enhance RNAi silencing of endogenous genes in two species

B. Hendrix, W. Zheng, M. J. Bauer, E. R. Havecker, J. T. Mai, P. H. Hoffer, R. Sanders, B. D. Eads, A. Caruano-Yzermans, D. N. Taylor, C. Hresko, J. Oakes, A. B. Iandolino, M. J. Bennett, J. Deikman

This study shows that 22 nt siRNAs induce stronger RNAi silencing and more transitive siRNAs in two plant species compared to 21 nt siRNAs.

bioRxiv · Apr 20, 2020Plant Biology