Author

N. Wadhwa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:bacteria (other)· 3 Research Focus:host-pathogen & immune response· 3 Assay:cryo-EM· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

H. C. Berg· 3 shared M. Erhardt· 2 shared M. Gosain· 2 shared M. Santiveri· 2 shared N. M. I. Taylor· 2 shared P. Kshetrapal· 2 shared R. Thiruvengadam· 2 shared S. Bhatnagar· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiophysics

H. C. Berg

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in vitro and in vivo

K. Jakhar, S. Sonar, G. Singh, T. R. Asuru, G. Joshi, N. Beniwal, T. Sarkar, M. Tiwari, J. Kaur, D. K. Rathore, B. Lal, S. Kumar, P. Srivastav, S. Kumar, V. Phagna, , S. Mani

The paper shows that SARS-CoV-2 spike antibodies can enhance DENV2 infection in vitro and in vivo, suggesting potential for increased dengue severity in COVID-19 survivors.

bioRxiv · Oct 9, 2023Immunology

Mechanisms of ion selectivity and rotor coupling in the bacterial flagellar sodium-driven stator unit

H. Hu, P. Popp, M. Santiveri, A. Eguiara, Y. Yan, Z. Liu, N. Wadhwa, Y. Wang, M. Erhardt, N. M. I. Taylor

This study determines the structure of the Na+-driven bacterial flagellar stator unit PomAB, revealing mechanisms of ion selectivity, rotor coupling, and stator unit activation.

bioRxiv · Nov 25, 2022 · PreprintMicrobiology

Ancestral SARS-CoV-2 driven antibody repertoire diversity in an unvaccinated individual correlates with expanded neutralization breadth

S. Deshpande, M. Y. Ansari, J. Sutar, P. Das, N. Hingankar, S. Mukherjee, P. Jayal, S. Singh, A. Anantharaj, J. Singh, S. Chattopadhyay, S. Raghavan, M. Gosain, S. Chauhan, S. Shrivas, , J. Bhattacharya

The paper examines antibody diversity in an unvaccinated SARS-CoV-2 infected individual, finding that post-vaccination neutralization breadth against Omicron variants is comparable to vaccinated individuals and breakthrough infections.

bioRxiv · Oct 19, 2022Immunology

A multi-state dynamic process confers mechano-adaptation to the bacterial flagellar motor

N. Wadhwa, A. S. Sassi, H. C. Berg, Y. Tu

The paper studies mechano-adaptation in bacterial flagellar motors by analyzing stator unit binding dynamics and proposes a minimal model explaining the observed behavior.

bioRxiv · Dec 22, 2021 · PreprintBiophysics

Mechanosensitive remodeling of the bacterial flagellar motor is independent of direction of rotation

N. Wadhwa, Y. Tu, H. C. Berg

The paper shows that the mechanosensitive remodeling of the bacterial flagellar motor depends on torque, not rotation direction, and presents a mathematical model to explain this behavior.

bioRxiv · Jan 19, 2021Biophysics

Structure and function of stator units of the bacterial flagellar motor

M. Santiveri, A. Roa-Eguiara, C. Kuhne, N. Wadhwa, H. C. Berg, M. Erhardt, N. M. I. Taylor

The paper presents cryo-EM structures of bacterial flagellar stator units in different states and proposes a mechanistic model for torque generation and direction switching.

bioRxiv · May 15, 2020Biophysics

Cell-intrinsic genetic regulation of peripheral memory-phenotype T cell frequencies

A. S. Chawla, P. Kanodia, A. Mukherjee, V. Jain, G. Kaur, P. Coshic, K. Chatterjee, N. Wadhwa, U. C. M. Natchu, S. Sopory, S. Bhatnagar, P. P. Majumder, A. George, V. Bal, S. Rath, S. B. Prabhu

The paper shows memory T cell frequencies are genetically regulated and stable over time, while recently activated cells are influenced by environmental factors.

bioRxiv · Jun 25, 2018Immunology