HLH-30/TFEB is necessary for chromatin reorganization and maintenance of cell quiescence during starvation in C. elegans
Marta Muñoz-Barrera, Alejandro Mata‐Cabana, Almudena Moreno-Rivero, Francine Piubeli, Beatriz Ren-Barroso, Nada Al-Refaie, Gabriel Gutiérrez, Daphne S. Cabianca, María Olmedo
This study shows HLH-30/TFEB is essential for chromatin reorganization and cell quiescence during starvation in C. elegans, with loss of HLH-30 disrupting cell cycle arrest and causing premature developmental activation.
Nucleic Acids Research · Sep 21, 2026Peer-reviewedDevelopmental Biology