Author

Naoko Sakagami

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Koji Mizuhashi· 2 shared Noriaki OnoiD· 2 shared Wanida OnoiD· 2 shared Yuki MatsushitaiD· 2 shared Annabelle Zhou· 1 shared Henry M. KronenbergiD· 1 shared Michael Fogge· 1 shared Mizuki NagataiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersDevelopmental Biology

Koji Mizuhashi

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2 papers

Recent·Most cited

Growth plate resting zone chondrocytes acquire transient clonal competency upon Hedgehog activation and efficiently transform into trabecular bone osteoblasts

Shion Orikasa, Yuki Matsushita, Michael Fogge, Koji Mizuhashi, Naoko Sakagami, Wanida Ono, Noriaki Ono

This study shows that Hedgehog activation in resting zone chondrocytes converts them into osteoblasts through clonal expansion and migration.

bioRxiv · May 31, 2023 · PreprintDevelopmental Biology

Chondrocytes in the resting zone of the growth plate are maintained in a Wnt-inhibitory environment

Shawn A. Hallett, Wanida Ono, Yuki Matsushita, Naoko Sakagami, Koji Mizuhashi, Nicha Tokavanich, Mizuki Nagata, Annabelle Zhou, Takao Hirai, Henry M. Kronenberg, Noriaki Ono

The paper identifies a Wnt-inhibitory environment maintaining resting zone chondrocytes and shows that Wnt activation disrupts their differentiation into columnar chondrocytes.

eLife · Jul 26, 2021Peer-reviewedDevelopmental Biology