Mizuki Nagata

This study shows that deleting SIK2/SIK3 in alveolar bone reduces bone formation and mass by impairing osteoblast maturation, unlike in long bones where it increases bone formation and mass.

The paper identifies a Wnt-inhibitory environment maintaining resting zone chondrocytes and shows that Wnt activation disrupts their differentiation into columnar chondrocytes.

The paper identifies Hes1 as a marker for early perichondrial skeletal progenitor cells using single-cell RNA-seq and lineage tracing in endochondral bone development.