Consumption of processed foods impairs memory function through dietary advanced glycation end-products
Anna Hayes, Molly E. Klug, Madhav Sharma, Alicia E. Kao, Shan Sun, Edwin De Jesus Lopez Gonzalez, Houming Zhu, Joshua C Dent, Richard J. Clark, David R. Sell, Deepitha Nelson, Vincent M. Monnier, Linda Tsan, Jessica J. Rea, Arun Ahuja, , Scott E. Kanoski
This study shows that an AGE-rich diet during adolescence impairs memory via hippocampal synaptic deficits and microbiome changes, which can be mitigated by AGE inhibitors.
bioRxiv · Jan 8, 2026 · PreprintNeuroscience