Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
Madalynn L. Erb, Kayla A. Sipple, Nathan D. Levine, Xi Chen, Darren J. Moore
This study shows that deleting ATP13A2 in adult mice leads to progressive dopaminergic degeneration and lysosomal issues, mimicking human neurodegenerative diseases.
npj Parkinson s Disease · Jul 19, 2024Peer-reviewedNeuroscience