Author

Nathan Ma

Sunnybrook Health Science Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert P. CheniD· 2 shared Biranavan UthayakumariD· 2 shared Charles H. CunninghamiD· 2 shared Chris HeyniD· 2 shared Hany SolimaniD· 2 shared Kayvan R. KeshariiD· 2 shared Nadia D. BragagnoloiD· 2 shared Nicole I. C. CappellettoiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Albert P. ChenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Microbial Metabolites Potentiate MAIT Cell Anti-Tumor Immunity Against Solid Tumors

Yichen Zhu, Xinyuan Shen, Yuning Chen, Nathan Ma, Catherine Zhang, Aiqi Zhao, Yanxin Tian, Shreya Gumate, Jie Huang, Siyu Lin, Aijun Wang, Vatche Garen Agopian, Yan-Ruide Li, Lili Yang

The paper shows microbial metabolites 5-OP-RU and 5-OE-RU activate MAIT cells to combat solid tumors by enhancing cytotoxicity, cytokine secretion, and reprogramming the tumor microenvironment.

bioRxiv · Jul 25, 2026 · PreprintCancer Biology

Task Activation Results in Regional 13C-Lactate Signal Increase in the Human Brain

Biranavan Uthayakumar, Nicole I. C. Cappelletto, Nadia D. Bragagnolo, Albert P. Chen, Nathan Ma, William J. Perks, Ruby Endre, Fred Tam, Simon J. Graham, Chris Heyn, Kayvan R. Keshari, Hany Soliman, Charles H. Cunningham

The paper uses HP-13C MRI to show increased 13C-lactate signal in brain regions activated during a visual task compared to a control condition.

Journal of Cerebral Blood Flow & Metabolism · Jan 25, 2025Peer-reviewedNeuroscience

Evidence of Lactate Shuttling in the Human Brain using Hyperpolarized 13C-MRI

Biranavan Uthayakumar, Hany Soliman, Albert P. Chen, Nadia D. Bragagnolo, Nicole I. C. Cappelletto, Ruby Endre, William J. Perks, Nathan Ma, Chris Heyn, Kayvan R. Keshari, Charles H. Cunningham

The paper tests lactate shuttling in the human brain using hyperpolarized 13C-MRI and finds that reducing lactate saturation increases bicarbonate signal, indicating lactate conversion to pyruvate and oxidation.

Magnetic Resonance in Medicine · Jan 17, 2024Peer-reviewedNeuroscience