Author

Yuning Chen

Chinese University of Hong KongPrimary ORCID profile (0000-0002-7358-7055 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Yuning CheniD2 papers · Boston University

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Adrian On-Wah LeungiD· 1 shared Aijun WangiD· 1 shared Aiqi ZhaoiD· 1 shared Catherine Zhang· 1 shared Chang LiiD· 1 shared Fujia Zhang· 1 shared Hoi‐Hung CheungiD· 1 shared Hong-Man Lin· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Adrian On-Wah LeungORCID

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2 papers

Recent·Most cited

Microbial Metabolites Potentiate MAIT Cell Anti-Tumor Immunity Against Solid Tumors

Yichen Zhu, Xinyuan Shen, Yuning Chen, Nathan Ma, Catherine Zhang, Aiqi Zhao, Yanxin Tian, Shreya Gumate, Jie Huang, Siyu Lin, Aijun Wang, Vatche Garen Agopian, Yan-Ruide Li, Lili Yang

The paper shows microbial metabolites 5-OP-RU and 5-OE-RU activate MAIT cells to combat solid tumors by enhancing cytotoxicity, cytokine secretion, and reprogramming the tumor microenvironment.

bioRxiv · Jul 25, 2026 · PreprintCancer Biology

RNA helicase Ddx21 safeguards fetal HSPC expansion by recruiting Kdm5a to epigenetically sustain ribosomal and hematopoietic gene transcription

Adrian On-Wah Leung, Chang Li, Xianyin Huang, Zhuming Fan, Yuning Chen, Jiaxing Liu, Hong-Man Lin, Xiaoming Cui, Fujia Zhang, Ruoxi Niu, Kam Tong Leung, Hoi‐Hung Cheung

This study identifies Ddx21's role in fetal hematopoiesis by showing it recruits Kdm5a to maintain epigenetic regulation of ribosomal and hematopoietic gene transcription, essential for HSPC expansion.

bioRxiv · Sep 4, 2025 · PreprintCell Biology