Author

Nele Vaes

KU Leuven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

Apeksha ShapetiiD· 2 shared Hans Van OosterwyckiD· 2 shared Ilse JonkersiD· 2 shared Jorge Barrasa FanoiD· 2 shared Laurens KimpsiD· 2 shared Rocío Castro-ViñuelasiD· 2 shared Alejandro Apolinar–FernándeziD· 1 shared Christ GlorieuxiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

Apeksha ShapetiORCID

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Author profile →

3 papers

Recent·Most cited

Interplay between canonical Wnt signaling and α5β1 integrins modulates mechanoresponse in human articular cartilage

Nuria Viudes-Sarrión, Rocío Castro-Viñuelas, Nele Vaes, Emma J. Blain, Rik Jozef Urbain Lories, Ilse Jonkers

This study investigates how Wnt signaling and α5β1 integrins interact to modulate mechanical responses in human cartilage, showing integrins mediate Wnt-driven changes in load responsiveness.

Osteoarthritis and Cartilage · Aug 1, 2026Peer-reviewedMolecular Biology

Osteoarthritic chondrocytes exert higher contractile forces and exhibit enhanced protrusive activity when cultured in 3D degradable hydrogels

Maxim Vovchenko, Nele Vaes, Jorge Barrasa Fano, Apeksha Shapeti, Rocío Castro-Viñuelas, Laurens Kimps, Christ Glorieux, Ilse Jonkers, Hans Van Oosterwyck

This study shows OA chondrocytes generate higher contractile forces in 3D degradable hydrogels compared to 2D, linked to increased protrusive activity and actomyosin engagement.

Acta Biomaterialia · Jan 3, 2026Peer-reviewedBioengineering

Data-driven traction force microscopy in 3D collagen hydrogels

Jorge Barrasa Fano, Laurens Kimps, Alejandro Apolinar–Fernández, Débora do Carmo Linhares, Iain Muntz, Elías Núñez-Ortega, Nele Vaes, Apeksha Shapeti, Ruth Cardinaels, Gijsje Hendrika Koenderink, Jose A. Sanz‐Herrera, Hans Van Oosterwyck

This paper introduces DD-TFM, a data-driven 3D traction force microscopy method that models collagen hydrogels as discrete fiber networks, revealing fiber-level matrix deformations caused by endothelial cells.

bioRxiv · Nov 17, 2025 · PreprintBiophysics