Metabolomic Response to Non-Steroidal Anti-Inflammatory Drugs
Soumita Ghosh, Nick Lahens, Kayla Barekat, Soon‐Yew Tang, Katherine N. Theken, Emanuela Ricciotti, Arjun Sengupta, Robin Joshi, Frederic D. Bushman, Aalim M. Weljie, Tilo Großer, Garret A. FitzGerald
This study compares the metabolomic effects of naproxen and celecoxib in humans and mice, finding that naproxen reduces tryptophan levels independently of Cox-2 inhibition.
bioRxiv · Nov 26, 2024 · PreprintSystems Biology