Tilo Großer

This study compares the metabolomic effects of naproxen and celecoxib in humans and mice, finding that naproxen reduces tryptophan levels independently of Cox-2 inhibition.

This study compares the genomic response of mouse aorta to proton and gamma radiation, finding differences in gene responsiveness and pathway activation.

The paper introduces a framework to rank genomic features by differential effect size, showing that pseudocounts optimize the balance between fold-change and difference sorting.

This study identifies differences in cyclooxygenase pathway activation and inflammatory biomarker levels as factors associated with variability in ibuprofen analgesic response following third-molar extraction.