Author

Nicolette A. Ender

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ji‐Hoon LeeiD· 3 shared Tanya T. PaulliD· 3 shared Seung Woo RyuiD· 2 shared Antony HarveyiD· 1 shared Carlos Tadeu Pagani ZaniniiD· 1 shared D. Chase PectoliD· 1 shared Jon M. HuibregtseiD· 1 shared Olivia M. ConwayiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

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10 top collaborators · 38 mutual co-author links

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3 shared papersMolecular Biology

Ji‐Hoon LeeORCID

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3 papers

Recent·Most cited

Regulation of transcription patterns, poly-ADP-ribose, and RNA-DNA hybrids by the ATM protein kinase

Phillip R. Woolley, Xuemei Wen, Olivia M. Conway, Nicolette A. Ender, Ji‐Hoon Lee, Tanya T. Paull

The paper shows ATM deficiency leads to transcription-associated lesions, affecting cerebellum function and causing neurodegeneration through changes in transcription and PARylation.

Cell Reports · Mar 1, 2024Peer-reviewedMolecular Biology

Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency

Ji‐Hoon Lee, Seung Woo Ryu, Nicolette A. Ender, Tanya T. Paull

The paper shows that PARP-driven protein aggregation occurs in ATM and Mre11 deficiency, leading to protein homeostasis loss and cerebellar dysfunction.

Molecular Cell · Feb 10, 2021Peer-reviewedMolecular Biology

Comprehensive identification of HSP70/HSC70 Chaperone Clients in Human Cells

Seung Woo Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji‐Hoon Lee, Carlos Tadeu Pagani Zanini, Antony Harvey, Jon M. Huibregtse, Peter J. Mueller, Tanya T. Paull

This study identifies HSP70 and HSC70 chaperone clients in human cells using a ubiquitin-mediated tagging strategy, revealing distinct client specificities and stress-induced changes.

PLoS Biology · Jul 20, 2020Peer-reviewedMolecular Biology