Author

Oshadi Wimalarathne

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Seung Woo RyuiD· 2 shared Tanya T. PaulliD· 2 shared Antony HarveyiD· 1 shared Carlos Tadeu Pagani ZaniniiD· 1 shared Chung-Hsuan Kao· 1 shared D. Chase PectoliD· 1 shared Ji‐Hoon LeeiD· 1 shared Jon M. HuibregtseiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Seung Woo RyuORCID

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2 papers

Recent·Most cited

Comprehensive identification of HSP70/HSC70 Chaperone Clients in Human Cells

Seung Woo Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji‐Hoon Lee, Carlos Tadeu Pagani Zanini, Antony Harvey, Jon M. Huibregtse, Peter J. Mueller, Tanya T. Paull

This study identifies HSP70 and HSC70 chaperone clients in human cells using a ubiquitin-mediated tagging strategy, revealing distinct client specificities and stress-induced changes.

PLoS Biology · Jul 20, 2020Peer-reviewedMolecular Biology

Growth-regulated Hsp70 phosphorylation regulates stress responses and prion maintenance

Chung-Hsuan Kao, Seung Woo Ryu, Min Ja Kim, Xuemei Wen, Oshadi Wimalarathne, Tanya T. Paull

This study shows that phosphorylation of Hsp70 at Ser151 by Cdk1 during growth reduces its chaperone activity and affects stress responses and prion maintenance.

Molecular and Cellular Biology · Mar 24, 2020Peer-reviewedMolecular Biology