Author

Yenan T. Bryceson

Karolinska InstitutetORCID 0000-0002-7783-9934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetic & Genomic Medicine· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Adem KarbuziD· 1 shared Adrian GervaisiD· 1 shared Agatha SchlüteriD· 1 shared Ahmad A. TarhiniiD· 1 shared Ahmad N. Abou TayouniD· 1 shared Ákos VégváriiD· 1 shared Alban Lermine· 1 shared Alessandro AiutiiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Adem KarbuzORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BCL11B targeting in tumor CD8+ T cells amplifies anti-tumor response by blocking exhaustion while promoting stemness and cytotoxicity

Leonardo Silvane, Τόμας Ζελένκα, Divya Priyanka Talada, Valeriu Bogdan Cismasiu, Shamima Islam, Raghwendra P. Singh, Zefanias Ngove, Sayan Chakraborty, MacLean S. Hall, Jamie L. Blauvelt, Erika Adriana Eksioglu, Soraya Zorro Manrique, Joseph Johnson, Alyssa Obermayer, Alex Alfaro, , Dorina Avram

This paper shows that reducing BCL11B in CD8+ T cells enhances anti-tumor response by preventing exhaustion and boosting stemness and cytotoxicity.

bioRxiv · Aug 7, 2026 · PreprintImmunology

ISG15-USP18 signaling restrains viperin-dependent metabolic antiviral restriction

Niklas L Kahler, Sefanit Rezene, Florine E. M. Scholte, Anoop T. Ambikan, Elisa Saccon, Vanessa Monteil, Prajakta Naval, Robin Macmillan, Simon Frick, Jenny Norén, Magda Lourda, Alì Mirazimi, Yenan T. Bryceson, Ronaldo Lira‐Junior, Vibhu Ranjan Prasad, , Soham Gupta

This study shows that ISG15-USP18 signaling limits viperin-dependent metabolic antiviral restriction by stabilizing USP18 and reducing viperin expression, thereby inhibiting viral replication.

bioRxiv · Mar 14, 2026 · PreprintMicrobiology

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with critical COVID-19

Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jérémy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, , Michel Vidaud

The paper identifies rare loss-of-function variants in type I IFN immunity genes associated with severe COVID-19, particularly in younger patients with recessive inheritance.

Genome Medicine · Apr 5, 2023Peer-reviewedGenetic & Genomic Medicine

Determination of essential phenotypic elements of clusters in high-dimensional entities - DEPECHE

Axel Theorell, Yenan T. Bryceson, Jakob Theorell

DEPECHE is a clustering algorithm that improves interpretability of single-cell data by retaining only relevant variables for cluster separation.

PLoS ONE · Mar 7, 2019Peer-reviewedBioinformatics