Author

Nina Claudino

German Cancer Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Thomas HöferiD· 4 shared Giulia Di MuzioiD· 2 shared Jana BerlandaiD· 2 shared Pei‐Chi WeiiD· 2 shared Sarah Benedetto· 2 shared Alessandro GrecoiD· 1 shared Alex IngiD· 1 shared Anna J. M. MarxiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersSystems Biology

Thomas HöferORCID

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4 papers

Recent·Most cited

The Onset of Myeloid Differentiation in Hematopoietic Progenitors In Vivo is Coordinated with S-phase Progression

Jonas Metz, Alessandro Greco, Larissa Frank, Nina Claudino, Hans-Reimer Rodewald, Thomas Höfer

This study shows that myeloid differentiation in hematopoietic progenitors starts during S phase and is linked to chromatin changes and HOXA9 activity.

bioRxiv · May 13, 2026 · PreprintSystems Biology

Recurrent DNA Break Clusters Regulated by Polymerase Theta Are Essential for Replication Stress Induced Copy Number Variation

Lorenzo Corazzi, Alex Ing, Vivien S. Ionasz, Anna J. M. Marx, Nathan Trausch, Sarah Benedetto, Giulia Di Muzio, Boyu Ding, Jana Berlanda, Marco Giaisi, Nina Claudino, Thomas Höfer, Pei‐Chi Wei

This study identifies recurrent DNA break clusters (RDCs) as causal factors for CNV formation under replication stress and shows DNA polymerase theta's role in preventing these events.

bioRxiv · Sep 1, 2025 · PreprintMolecular Biology

Adaptive Clonal Expansion Shapes Brain Development

Giulia Di Muzio, Sarah Benedetto, Li-Chin Wang, Lea Weber, Franciscus van der Hoeven, Brittney Armstrong, Hsin-Jui Lu, Jana Berlanda, Verena Körber, Nina Claudino, Michelle Krogemann, Thomas Höfer, Pei‐Chi Wei

The paper investigates NSPC proliferation dynamics in a mouse model, finding that adaptive clonal expansion by a small fraction of NSPCs can regenerate the entire neuronal population.

bioRxiv · Mar 4, 2025 · PreprintDevelopmental Biology

Long-range memory of growth and cycle progression correlates cell cycles in lineage trees

Erika E Kuchen, Nils B. Becker, Nina Claudino, Thomas Höfer

The paper shows that cell cycle length correlations in lineage trees reveal growth's role in controlling proliferation, identifying cell size and division license as key factors.

bioRxiv · Jul 24, 2018 · PreprintSystems Biology