Nils B. Becker

This study identifies a mechanism of asynchronous nuclear division in Plasmodium falciparum that enhances proliferation by minimizing resource idling through sequential allocation of a limiting replication resource.

The paper traces individual PGC clones in mice to show early stochastic bottlenecks shape clonal contributions and reproductive success.

The paper uses fate-mapping, single-cell RNA-sequencing, and computational methods to show that major hematopoietic lineages diverge within HSCs, identifying a self-renewing HSC subpopulation and a direct thrombopoiesis pathway.

The paper shows that cell cycle length correlations in lineage trees reveal growth's role in controlling proliferation, identifying cell size and division license as key factors.