Author

Michiel J. Thiecke

Amsterdam UMC Location Vrije Universiteit AmsterdamORCID 0000-0001-8902-7709Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adri A.M. Thomas· 1 shared Daniel Voltolini‐González· 1 shared Douwe Molenaar BiD· 1 shared Eduard A. Struijs· 1 shared Emiel Polder· 1 shared Ermelinda Jaku· 1 shared Gordana WutziD· 1 shared Hein Fritsen· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adri A.M. Thomas

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Author profile →

2 papers

Recent·Most cited

Cohesin-dependent and independent mechanisms support chromosomal contacts between promoters and enhancers

Michiel J. Thiecke, Gordana Wutz, Matthias Muhar, Wen Tang, Stephen Bevan, Valeriya Malysheva, Roman R. Stocsits, Tobias Neumann, Johannes A. Zuber, Peter Fraser, Stefan Schoenfelder, Jan‐Michael Peters, Mikhail Spivakov

The paper investigates chromosomal contacts between promoters and enhancers using Capture Hi-C, showing that cohesin depletion affects long-range contacts but not shorter-range ones.

Cell Reports · Jul 1, 2020Peer-reviewedGenomics

Integrated Stress Response Deregulation underlies Vanishing White Matter and is a target for therapy

Truus E. M. Abbink, Lisanne E. Wisse, Ermelinda Jaku, Michiel J. Thiecke, Daniel Voltolini‐González, Hein Fritsen, Sander Bobeldijk, Timo J. ter Braak, Emiel Polder, Nienke L. Postma, Marianna Bugiani, Eduard A. Struijs, Mark H. G. Verheijen, Nina Straat, Sophie van der Sluis, , Marjo S. van der Knaap

ISRIB ameliorates ISR deregulation and clinical signs in VWM mice.

bioRxiv · Dec 4, 2018 · PreprintNeuroscience