Author

O. Hajihassani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. J. Graor· 4 shared J. J. Hue· 4 shared J. M. Winter· 4 shared M. Zarei· 4 shared A. Vaziri-Gohar· 3 shared L. D. Rothermel· 2 shared M. Rathore· 2 shared A. Abbas· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersCancer Biology

H. J. Graor

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4 papers

Recent·Most cited

Targeting wild-type IDH1 enhances chemosensitivity in pancreatic cancer

M. Zarei, O. Hajihassani, J. J. Hue, H. J. Graor, L. D. Rothermel, J. M. Winter

This study shows that targeting wild-type IDH1 enhances chemosensitivity in pancreatic cancer by disrupting redox balance and increasing ROS-induced apoptosis.

bioRxiv · Mar 29, 2023Cancer Biology

Surgical techniques and tips for a reliable murine model of primary and metastatic pancreatic cancer

J. J. Hue, M. Zarei, H. J. Graor, O. Hajihassani, E. S. Katayama, A. W. Loftus, A. Vaziri-Gohar, J. M. Winter

The paper provides detailed surgical techniques for orthotopic and splenic injections in a murine model of pancreatic cancer to improve preclinical research accuracy.

bioRxiv · Jul 30, 2022 · PreprintCancer Biology

Wild-type IDH1 inhibition enhances chemotherapy response in melanoma

M. Zarei, O. Hajihassani, J. J. Hue, H. J. Graor, M. Rathore, A. Vaziri-Gohar, J. M. Asara, J. M. Winter, L. D. Rothermel

This study shows that inhibiting wild-type IDH1 enhances chemotherapy response in melanoma by reducing redox homeostasis and increasing reactive oxygen species.

bioRxiv · May 13, 2022Cancer Biology

Increased glucose availability sensitizes pancreatic cancer to chemotherapy

A. Vaziri-Gohar, J. J. Hue, H. J. Graor, A. Abbas, M. Zarei, O. Hajihassani, G. Titomihelakis, J. Feczko, M. Rathore, R. Wang, M. Zarei, M. Goudarzi, R. Zhang, B. Willard, L. Zhang, , J. M. Winter

This study shows that high glucose levels increase the effectiveness of chemotherapy in pancreatic cancer by reducing glutathione biosynthesis, which enhances oxidative stress in cancer cells.

bioRxiv · Apr 29, 2022Cancer Biology