Author

O. Melnyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

J. Vicogne· 2 shared A. K. Linnemann· 1 shared A. Mougel· 1 shared A. N. Novak· 1 shared B. Duffett· 1 shared B. Leclerc· 1 shared C. Dissous· 1 shared C. Muralidharan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioengineering

J. Vicogne

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Real Time In vivo Analysis of Pancreatic Beta-cell Autophagic Flux Reveals Impairment Before Onset of Autoimmune Diabetes

O. Melnyk, C. Muralidharan, B. Duffett, A. N. Novak, G. Perez-Aviles, M. M. Martinez, J. J. Crowder, A. K. Linnemann

This study uses intravital microscopy to show autophagic flux defects in NOD mouse beta-cells before hyperglycemia onset, suggesting a causal role in T1D pathogenesis.

bioRxiv · May 23, 2023 · PreprintCell Biology

A Self-Purifying Microfluidic System for Identifying Drugs Acting Against Adult Schistosomes

V. Girod, M.-J. Ghoris, S. Caby, C. Dissous, O. Melnyk, V. Senez, J. Vicogne

This paper introduces a microfluidic system for identifying antischistosomal drugs by selecting healthy adult worms and detecting compound activity through detachment readouts.

bioRxiv · Apr 4, 2022Bioengineering

Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent minimal MET receptor agonist.

G. de Nola, B. Leclerc, A. Mougel, S. Dezitter-Taront, C. Simonneau, F. Forneris, E. Adriaenssens, H. Drobecq, O. Melnyk, E. Gherardi, H. de Jonge, J. Vicogne

This study designs and characterizes K1K1, a minimal MET receptor agonist made from two kringle 1 domains of HGF/SF, showing stability and biological activity comparable to native HGF/SF in vitro and in a mouse liver disease model.

bioRxiv · Jul 20, 2020Bioengineering