Author

O. P. Duddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 4 Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Assay:metagenomics· 1

Frequent Co-Authors

B. L. Bassler· 4 shared J. E. Silpe· 4 shared X. Huang· 2 shared A. A. Bridges· 1 shared B. R. Henke· 1 shared D. R. Coronado· 1 shared F. A. Hussain· 1 shared J. Cong· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMicrobiology

B. L. Bassler

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4 papers

Recent·Most cited

Natural and synthetic inhibitors of a phage-encoded quorum-sensing receptor affect phage-host dynamics in mixed bacterial communities

J. E. Silpe, O. P. Duddy, B. L. Bassler

The paper shows that a phage-encoded quorum-sensing receptor is activated by its host's autoinducer and inhibited by non-cognate autoinducers and synthetic inhibitors, affecting phage-host dynamics in bacterial communities.

bioRxiv · Oct 18, 2022Microbiology

Small protein modules dictate prophage fates during polylysogeny

J. E. Silpe, O. P. Duddy, F. A. Hussain, K. J. Forsberg, B. L. Bassler

The paper identifies small protein modules in phages that independently control prophage induction without relying on DNA damage cues, revealing alternative pathways for lysis in polylysogeny.

bioRxiv · Sep 16, 2022Microbiology

Mechanism underlying autoinducer recognition in the Vibrio cholerae DPO-VqmA quorum-sensing pathway

X. Huang, O. P. Duddy, J. E. Silpe, J. P. Paczkowski, J. Cong, B. R. Henke, B. L. Bassler

The paper investigates the DPO-VqmA quorum-sensing pathway in Vibrio cholerae, revealing DPO-dependent and -independent activities of VqmA and structural insights into ligand binding.

bioRxiv · Dec 19, 2019Microbiology

Separating Functions of the Phage-Encoded Quorum-Sensing-Activated Antirepressor Qtip

J. E. Silpe, A. A. Bridges, X. Huang, D. R. Coronado, O. P. Duddy, B. L. Bassler

This study identifies Qtip as a phage-encoded antirepressor that disrupts prophage repressor function and localizes to bacterial poles, revealing distinct mechanisms of quorum-sensing activation.

bioRxiv · Dec 16, 2019Microbiology