Author

Olaf L. Cotugno

Utrecht University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Annet C. W. van Wesel· 1 shared Antonio Garcia-GuerraiD· 1 shared Charlotte V. HegemaniD· 1 shared Enrico MastrobattistaiD· 1 shared Esmeralda BosmaniD· 1 shared Ingmar Y. de Groot· 1 shared Ivana Lansweers· 1 shared Jerney J. Gitz-Francois· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Annet C. W. van Wesel

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Author profile →

1 paper

Recent·Most cited

A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release

Omnia M. Elsharkasy, Charlotte V. Hegeman, Tom A. P. Driedonks, Xiuming Liang, Ivana Lansweers, Olaf L. Cotugno, Ingmar Y. de Groot, Zoë E. M. N. J. de Wit, Antonio Garcia-Guerra, Niels J. A. Moorman, Sjoerd H. Boonstra, Esmeralda Bosman, Juliet W. Lefferts, Willemijn S. de Voogt, Jerney J. Gitz-Francois, , Olivier G. de Jong

This paper develops a modular strategy for delivering CRISPR-Cas9 via extracellular vesicles using aptamer-based loading and UV-activated cargo release, demonstrating efficient delivery and versatility in Cas9 variants.

Nature Communications · Nov 21, 2025Peer-reviewedMolecular Biology